Fri Feb 20 2026

40 articles - From Friday Feb 13 2026 to Friday Feb 20 2026

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis
Advanced therapies for inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and meta-analysis.

Advanced therapies show efficacy and comparable safety in IBD-PSC. The study findings are limited by significant heterogeneity and further prospective studies with standardized endpoints are needed.

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Dysplasia detection using high-definition scopes with dye vs virtual chromoendoscopy in IBD: A meta-analysis of randomized clinical trials.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.

Plasma choline and betaine concentrations discriminate low vs AI under controlled feeding. These findings support targeted metabolite profiling to improve choline intake assessment and reveal individual differences in liver response to low choline intake. Clinical trials registry Choline Nutritional Status Development of a Biomarker Panel; NCT03726671 ( ) registered 2018-10-31.

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Diet Quality and All-Cause Mortality Among Individuals with Chronic Kidney Disease: A UK Biobank Cohort Study.

In this cohort study of middle-aged and older adults with CKD, higher adherence to healthy dietary patterns, including aMED, DASH, and AHEI-2010, was associated with significantly lower all-cause mortality, whereas higher DII scores were linked to higher mortality. These findings highlight diet quality as a modifiable protective factor in individuals with CKD.

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Impact of the COVID-19 pandemic on prenatal Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) participation: analysis of Pregnancy Risk Assessment Monitoring System 2017-2022 data.

Findings suggest a decline in prenatal WIC participation after the pandemic. Additionally, the association of the pandemic with lower odds of WIC participation among those from lower socioeconomic status and poorer health care access suggests exacerbation of health disparities and underscores the need to improve participation in these groups.

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Metabolic impact of reduced-protein Nordic diet-based complementary feeding: a secondary analysis of a randomized controlled study.

Complementary feeding during infancy substantially shapes the plasma metabolome. Reducing protein intake from complementary feeding helps attenuate rapid infant weight gain, a well-established early-life predictor of later obesity. Clinical trail registration This study was registered at ClinicalTrials.gov as NCT02634749.

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Inflamm Bowel Dis
Acute severe ulcerative colitis without systemic toxicity: A retrospective multicenter cohort study suggesting refining the definition of acute severe ulcerative colitis.

Non-TW ASUC shows a disease course and outcomes comparable to TW ASUC, underscoring an equally severe and comparable condition. These findings emphasize a need to broaden ASUC definitions to reflect contemporary practice.

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Artificial intelligence enhances screening efficiency for inflammatory bowel disease clinical trials: a prospective study.

An LLM-based AI tool significantly improved identification of potentially eligible patients and screening efficiency for IBD clinical trials, outperforming physician referrals by screening electronic medical records and generating ranked candidate lists based on trial inclusion/exclusion criteria, thereby enhancing trial recruitment.

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Characterization of mesocolic adipose hyperplasia in a rat 2,4,6-trinitrobenzenesulfonic acid colitis model and comparison to creeping fat in Crohn disease.

Mesocolic hyperplasia, closely replicating the key histopathological and molecular features of CD-related CrF, developed in half of the rats in this model. This model provides a cost-effective platform for studying the interplay between intestinal inflammation and mesenteric adipose tissue remodeling.

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Electroacupuncture at Baliao Points Alleviates Ulcerative Colitis via α7nAChR-Mediated Macrophage Polarization and Gut Microbiota Modulation.

Heart rate variability analysis indicated enhanced vagal activity post-EA. Collectively, these findings demonstrate that EA at the Baliao acupoints alleviates experimental UC via α7nAChR-dependent facilitation of M2 macrophage polarization and restoration of a healthy gut microbiota, highlighting a promising neuromodulation-based approach for UC treatment.

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Integrated long-term safety of 10-year ozanimod treatment: results from clinical trials in patients with moderate-to-severe ulcerative colitis or relapsing multiple sclerosis.

Long-term exposure to ozanimod is well tolerated in patients with moderate to severe UC or RMS, confirming the previously established safety profile of ozanimod. Clinical trial registry NCT01647516; NCT02435992; NCT02576717.

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Persistent Abdominal Pain in Patients with Inactive Inflammatory Bowel Disease: A Clinical Conundrum.

Emerging evidence suggests that such pain may result from complex interactions involving visceral hypersensitivity, alterations in the enteric nervous system, central sensitization, dysregulation of the gut-brain axis, and psychosocial factors, rather than ongoing mucosal inflammation. This review explores the multifactorial pathophysiology underlying persistent abdominal pain in inflammatory bowel disease remission and highlights the need for a comprehensive, biopsychosocial approach to diagnosis and treatment.

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Safety and outcomes of advanced IBD therapies in patients with HIV: a propensity-matched cohort analysis.

and relevance In this large multicenter cohort, AT use in HIV-IBD was rare but not associated with higher risks of infection, cancer, surgery, or death. These findings support the safety of AT in this population.

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J Crohns Colitis
Cutaneous autoimmune blistering disease during mirikizumab therapy in a patient with ulcerative colitis: a new potential trigger?

This case highlights that mirikizumab may represent a potential trigger of an AIBD in susceptible individuals with UC. Clinicians should be aware of this rare but relevant complication to ensure timely recognition and management.

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Tunnel vision: Rethinking local therapy for perianal fistulas in Crohn's disease.

There is an unmet need to generate novel local therapies that achieve long-lasting fistula closure. To facilitate their development, the delineation of host and microbial pathways contributing to PFCD pathogenesis and research in drug delivery systems are needed.

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Liver Transpl
A pilot randomized controlled trial of a transportation assistance program in liver transplant (TAP-LT) candidates.

Our pilot trial demonstrates Lyft rideshares to be feasible and highly acceptable to LT candidates (ClinicalTrials.gov, Number NCT05080595), supporting conduct of a larger efficacy trial.

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Pancreas
Evaluation of Malignant Predictive in Pancreatic Intraductal Papillary Mucinous Neoplasm Using Diffusion-weighted Imaging and Apparent Diffusion Coefficient Values: A Comparative Analysis With Histopathology.

DWI and ADC mapping are valuable diagnostic tools for differentiating benign and malignant IPMNs. These modalities can complement existing diagnostic criteria, reduce unnecessary surgeries, and enhance clinical decision-making.

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Pancreatology
Early direct admission to tertiary hospital specialized care reduces risk of severe acute pancreatitis: A propensity score-matched retrospective cohort study.

DST independently increases SAP risk. Early direct admission to tertiary specialized care reduces SAP risk by 38%, providing high-level evidence for optimizing AP management pathways, particularly prioritizing rapid referral for obese and alcohol-using populations.

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Prognostic and recurrence implications of subdividing WHO grade 2 pancreatic neuroendocrine tumors at a 10% Ki-67 threshold.

Subclassification of WHO G2 pNETs using a 10% Ki-67 threshold enhances postoperative risk stratification. When integrated with established pathological factors, this approach may better identify patients at increased risk of recurrence following curative resection.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Inflamm Bowel Dis
Considerations regarding the use of computer-aided detection in IBD surveillance colonoscopy.

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Crypt branching in IBD: from histologic marker to digital pathology opportunity.

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J Crohns Colitis
Attaining sustainability in inflammatory bowel disease.

We further highlight strategies to reduce harm while preserving-and potentially enhancing-patient outcomes. A clear understanding of sustainable IBD care is what enables the transition from fragmented efforts to coordinated, evidence-based strategies that can support both patient care and planetary health.

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Equitable access to inflammatory bowel disease care: challenges, strategies, and future directions.

Global partnerships are needed to build capacity where it is lacking. Achieving equitable access to IBD care will require coordinated action between clinicians, policy-makers, patients, and industry to ensure sustainable, patient-centered, and inclusive care worldwide.

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Holistic care in inflammatory bowel disease: is it in REACH?

Additionally, digital health technologies have provided diagnostic and therapeutic insights into advancing IBD care, enhancing the delivery of longitudinal, patient-centered care. To improve long-term outcomes and enhance quality of life for individuals with IBD, clinicians and healthcare systems must prioritize the development and integration of holistic, multidisciplinary care models into routine practice.

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REACH: C-cause.

Efforts to elucidate these integrated pathways have underscored the importance of both intrinsic host factors and extrinsic environmental triggers in IBD pathogenesis. Despite this, a better understanding of disease mechanisms is still needed, and will be essential to developing better therapies that can target relevant axes of the disease process and restore immune balance, facilitate tissue repair, and induce lasting remission.

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Rapid diagnosis and treatment of inflammatory bowel diseases.

Several recent studies have addressed the role of early diagnosis and early treatment, including differences to consider between Crohn's disease and ulcerative colitis. In this review we summarize the important insights obtained and highlight how outcomes for patients can be improved with a focus on timely diagnosis and timely, effective treatment interventions.

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Pancreas
Advances in Glucocorticoid Therapy for Acute Pancreatitis: A Review.

GCs exhibit potential in the management of AP by modulating inflammatory pathways and immune responses. Their use necessitates thorough risk assessment. Large-scale clinical trials are essential to establish standardized protocols, optimal dosing regimens, and patient selection criteria for GCs therapy in AP.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis
The long game in ulcerative colitis: mirikizumab's four-year outcomes.

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J Crohns Colitis
REACHing forward-a strategic vision for ECCO and the future of IBD care.

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Liver Transpl
A new HOPE for RAPID procedure: First clinical use of a DCD split graft with hypothermic perfusion support.

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Beyond the operating room: Long-Term care for living liver donors.

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Integrated care is necessary, but not sufficient, for equity in hepatocellular carcinoma outcomes.

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Letter to editor: Graft inflow modulation by splenic artery ligation in live donor liver transplant recipients in different time frames: A parallax!

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Letter to the Editor: Importance of establishing anatomical and physiological portal inflow during liver transplant in presence of portal vein thrombosis.

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Letter to the Editor: Interpreting living-donor liver transplantation outcomes in portal vein thrombosis.

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Pancreas
Clinical Characteristics of Acute and Chronic Pancreatitis in Children and Impact of Obesity.

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Pancreatology
Acute pancreatitis management and outcome at tertiary hospitals in Rwanda: A prospective multicenter study.

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Longitudinal clinical characteristics of misfolding-induced hereditary pancreatitis caused by PRSS1 p.L104P variant in a Hungarian family.

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Prospective long-term assessment of pulmonary impairment in chronic pancreatitis: A comparative study with healthy controls (RespPanc).

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Letters&Replies

Letters to the editors and authors’ replies

Inflamm Bowel Dis
Reply: "A methodological concern regarding small-sample propensity score matching and overfitting in the study of postoperative biologic strategies for Crohn's disease".

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